Look for the catalog of 2020-21IntroSems to roll out here in August.
Introductory Seminars for First-Year Students
Mitochondrial Transport and Function in Neuronal Health and Death
As our population continues to grow older, age-dependent neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and ALS are becoming more prevalent and thus pose a danger to public health nationwide. Effective treatments are desperately needed, however, we still know very little about how neurons die in those diseases. One organelle that is especially important to neuronal health is mitochondria, the power plant for the cell. In this IntroSem, we will learn how neurons employ molecular machinery to regulate, transport, and distribute mitochondria, and importantly, how these fundamental regulations are compromised in neurological disorders. Students will participate in hands-on labs to learn imaging mitochondrial transport in live cells using confocal microscopy. The labs will take place during class time and are located at the beautiful Arastradero campus, which is easily accessible by bike or the free Marguerite shuttle and provides a unique opportunity for freshmen to explore Stanford campuses and adjacent areas.